Fixed assets are stated at cost and depreciated using the straight-line method, based on useful lives as follows (in thousands):
 
Estimated
Useful Life (years)
As of December 31,
Asset Description20252024
Building39$10,437 $— 
LandNA1,963 — 
Laboratory equipment
7
39,127 26,753 
Furniture and fixtures
7
6,428 6,428 
Computer hardware and software
3 - 5
8,425 6,485 
Office equipment
7
171 171 
Manufacturing equipment
7
1,336 1,336 
Leasehold improvements
2 - 10
53,400 38,058 
Construction in progress42,410 51,127 
 163,697 130,358 
Less accumulated depreciation (60,755)(50,306)
 $102,942 $80,052 

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.